The Genomics Centre will carry out a complete genomic characterisation of the "Moli-sani" study, carried out by the Istituto Neurologico del Mediterraneo - Neuromed IRCCS.
Moli-sani is a study aimed at assessing risk/protective factors (e.g. environmental, genetic, biomolecular) related to chronic degenerative diseases - with particular regard to cancer, cardiovascular diseases and their intermediate phenotypes including hypertension, diabetes, dyslipidemia, obesity and metabolic syndrome. Between 2005 and 2010, the study recruited more than 24,000 people aged ≥35 years in the Molise region. Participants in the Moli-sani study underwent intensive phenotypic screening and biological samples were collected and stored in a dedicated biobank.
- Autism disorders and intellectual disability
The Centre for Neurogenomics will collaborate with the IRCCS Associazione Oasi Maria Santissima in Troina, Sicily - integrated within the main world consortia - which has recruited over 1500 patients suffering from Autism Spectrum Disorder / Intellectual Disability, on highly sophisticated neurobiology studies aimed at understanding the genetic and epigenetic mechanisms that are activated during brain development, even at the level of a single cell, and at correlating them with phenotyping data obtained through imaging techniques.
- Data enhancement from the national healthcare card
The Centre for Computational Biology and the Analysis, Decisions and Society Centre
are working on a highly strategic project whose aim is to access and analyse citizens' health data in the Health Card System, which contains the personal data and medical expenditure data of each individual citizen, from pharmacy purchases to surgeries and doctor visits. The data collected by Health Cards can be used to build predictive models of health status and future events at both individual and population level.